There are a number of groups I’m working with on research projects for open hardware and open biology for diagnostic testing, in light of COVID but also developing tests for diseases like typhoid with partners at MboaLab in Cameroon and elsewhere.
A stumbling block that is hitting detection hardware across several projects is photodiode circuit design, basically we do not have the right skillset to tackle this professionally and it’s a blocker!
One specific device with a high priority issue outstanding is Miriam, an open-source instrument for isothermal amplification reactions such as LAMP and realtime fluorescence detection. It would be super-helpful across a range of projects.
Andrew Straw’s lab (https://strawlab.org/) at the University of Freiburg have been fixing up some of the outstanding design issues but they’ve hit a roadblock on this one:
Would anyone have the expertise to help out with this? You’d be assisting a network of at least a dozen research labs working on low-cost and open biology, with the potential for this to be useful for many more.